Senior Theses
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Last Updated: 2023-11-27
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At Hanover College, a Senior Thesis is often required by departments as the culminating experience in their major program. These projects introduce students to the practice of a discipline by allowing them to conduct a serious scholarly project under the supervision of a faculty member. Students must file a copy of the completed Senior Thesis with the Duggan Library. Senior theses from 2017 to the present are available online through the Hanover College Digital Collections. Works from prior years, and for students who opted out of online access to their works, are available in the Duggan Library. Users can find records of all Senior Theses by searching the Library Catalog at https://libguides.hanover.edu.- Total items
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392
Works (391)
1. 1 Efficacy of R-Ketamine and (2R-6R)-Hydroxynorketamine in Alleviating Biochemical and Behavioral Manifestations of OCD in Mice.
- Title Tesim:
- 1 Efficacy of R-Ketamine and (2R-6R)-Hydroxynorketamine in Alleviating Biochemical and Behavioral Manifestations of OCD in Mice.
- Abstract Tesim:
- The prevalence of depression has risen by almost 50% worldwide from 1990 to 2017, leading to increased economic burden and reduced lifespans of those affected by an average of 12.7 years.1,2,3 This trend has necessitated research into treatments more effective than SSRIs and SNRIs, which are the most common antidepressants used today.4 Ketamine, an anesthetic drug with dissociative and hallucinogenic effects, alleviates depression symptoms far more rapidly than SSRIs, which take months to work, decreasing MARDS scores by almost eight more points than placebo 24 hours after treatment.10 Previous research has indicated that the R-enantiomer of ketamine improves mice outcomes in antidepressant-predictive tasks more effectively than S-ketamine.13 Additionally, data has demonstrated that (2R-6R)-HNK, an R-ketamine metabolite, is important for R-ketamine's antidepressant effects.14 OCD is often comorbid with depression and is often treated with SSRIs.7 Furthermore, since both disorders often exhibit reduced serotonin synthesis capacity, the two disorders may share similarities in mechanism.6,9 The study will assess the viability of the quinpirole-induced compulsive checking or QICC model for OCD treatment research, the effectiveness of R-ketamine at reducing compulsive behaviors in QICC mice compared to placebo and the SSRI paroxetine, and the role of the metabolite (2R-6R)-HNK in R-ketamine's efficacy in reducing compulsive checking behaviors in QICC mice. In this experiment, mice will be treated with either saline or quinpirole twice weekly for five weeks to create healthy control and QICC groups. When mice are treated with quinpirole, compulsive behaviors in mice such as frequent returns to specific places, shorter time intervals returning to preferred places, and fewer visits to non-preferred places are increased when compared to healthy controls.19 In these two groups, mice will be treated with either saline, the SSRI paroxetine, R-ketamine, or R)-d2-ketamine, an R-ketamine molecule altered to impede metabolism to (2R, 6R)-HNK. To monitor changes in compulsive checking behaviors, open-field tests will be performed on each mouse one hour, one day, and one week after treatment Additionally, changes in serotonin concentration in the raphé nuclei, the brain's primary area of serotonin production, will be tracked with microdialysis with analysis using HPLC-ECD. While R-ketamine, (R)-d2-ketamine, and paroxetine are all expected to reduce compulsive checking behaviors in QICC mice to levels similar to healthy control mice, R-ketamine is predicted to be the most effective. Similarly, while R-ketamine, (R)-d2-ketamine, and paroxetine are all expected to increase serotonin concentration in mice raphé nuclei, R ketamine is predicted to cause the greatest increase in serotonin concentration. If data indicates that R-ketamine is more effective than paroxetine at reducing compulsive checking behavior and increasing serotonin levels in QICC mice, R-ketamine should be considered in future research as a prospective OCD treatment. Furthermore, if R-ketamine is more effective than (R)-d2-ketamine at reducing compulsive checking behaviors and increasing serotonin concentration in QICC mice, (2R, 6R)-HNK may be important for R-ketamine's function as an OCD treatment.
- Creator:
- Wood, Lauren (HC 2024)
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS24_24
- Type:
- Book
- Keyword:
- Senior Theses
- Date Created:
- 2024
2. The 21st Century Impasse.
- Title Tesim:
- The 21st Century Impasse.
- Abstract Tesim:
- There are opposing sentiments deeply rooted in the cultures of the American and Russian peoples, and these sentiments, fed from within, grow stronger every year, further hindering reparation of the relationship between the two states. Three primary influences of both nations are government officials, media, and the entertainment industry. The first, government officials, includes such figures as the presidents, prime minister, secretary of state (in the US), and foreign minister (in Russia); ultimately, these leaders’ words have condemned the relationship with negativity, cynicism, and fatigue. The second, the press, is represented by key news sources (television, newspaper, and magazine) in both countries; what they say about the other country over the same eight-year period of time is reflective of the words of the officials. The press is also very critical and perhaps even aggressively opposed in its view of the relationship and the other country as a whole. The final source of input into the two cultures is the entertainment industry in both countries, primarily cinema and television shows, but including smaller subsets of the industry; entertainment used as a medium of propaganda occurred far more frequently on the American side of the relationship. Ultimately, the conclusion is that all three of these inputs into the societies are levelled against reparation and will work against it for the foreseeable future.
- Creator:
- Ball, Caleb (HC 2017)
- Date:
- 2017
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 17-008
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2017
3. Abigail Rinck, Voice Recital
- Title Tesim:
- Abigail Rinck, Voice Recital
- Creator:
- Rinck, Abigail Snow (HC 2018)
- Date:
- 2018
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 18-51
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2018
4. Absurd Aesthetics.
- Title Tesim:
- Absurd Aesthetics.
- Abstract Tesim:
- The concern of this work is to answer the following question: what is the value of art? To answer this question, it must be divided into two parts which must be answered in turn, and only then will the overall answer begin to show itself. The inquiry of this work requires that values be established first, and secondly a definition of art to be stated. For a guide to what value is, The Myth of Sisyphus by Albert Camus will be reviewed. This will establish an ethical standpoint from which we may develop art’s function (value) within human living. Before this utility can be found, however, we must establish what is art and what is not. It may at first seem intuitive to distinguish art from that which is not art to humans. Anyone seems to be able to look at an object which is painted and say that this object is art. Yet, some interesting cases develop which confuse our intuitions.
- Creator:
- Odulio, Jacob (HC 2019)
- Date:
- 2019
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 19-44
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2019
5. The Accelerated Aging of Whiskey.
- Title Tesim:
- The Accelerated Aging of Whiskey.
- Abstract Tesim:
- Moonshine was placed in containers with wood chips that were either charred, microwaved, or both. The aged product was analyzed using High Performance Liquid Chromatography. The samples were then compared against vanillin standards and commercial whiskey. The results show that several methods of wood preparation did in fact produce vanillin in the final product, successfully accelerating the aging of whiskey.
- Creator:
- Rinck, Abigail (HC 2018)
- Date:
- 2018
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 18-50
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2018
6. The Acceptance of the Non-Traditional Workstation by College Students.
- Title Tesim:
- The Acceptance of the Non-Traditional Workstation by College Students.
- Abstract Tesim:
- The purpose of this research was to measure the general acceptance of a non traditional work station on the Hanover College campus. Six Hanover students worked on the WorkFit and participated in a survey to measure likeness and preference of a non-traditional station. Data suggested that the non-traditional WorkFit is preferred over a traditional desk, however there is common discomfort due to location and mechanisms of the WorkFit bike.
- Creator:
- Little, Tynisha (HC 2018)
- Date:
- 2018
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 18-35
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2018
7. The Accuracy of Apple Watch Caloric Expenditure during Exercise
- Title Tesim:
- The Accuracy of Apple Watch Caloric Expenditure during Exercise
- Abstract Tesim:
- The purpose of this study was to determine the accuracy of the Apple Watch in regards to caloric expenditure during varying forms of exercise. The Apple Watch is one of the main smart watches that is able to track caloric expenditure, but how accurate is it? Three subjects who owned an Apple Watch participated in this study. Each subject performed two trials of walking, cycling, and arm cranking for 10 minutes, while at a heart rate of 120 bpm. The subject wore the headgear, mouthpiece and nose piece that was associated with the Parvo Metabolic Cart. The Parvo Metabolic Cart was calibrated before each trial. The data from all three subjects was compiled into means to determine the reliability, relative accuracy, and absolute accuracy. the data suggests that the Parvo Metabolic Cart and the Apple Watch were both reliable and relatively accurate in providing the Kcal expenditure. The data from this study suggested that the Apple Watch had absolute accuracy when predicting Kcals for walking. However, the data suggested the Apple Watch did not have absolute accuracy for cycling and arm cranking. The data suggested that this was because the Apple Watch was based on a heart rate formula, and was not able to measure oxygen consumption, R-Value, and muscle size.
- Creator:
- Breeding, Anne
- Date:
- 2022
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 22-25
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2022
8. Accuracy of the Charge HR Fitbit : Step Count, Distance, Heart Rate, and Floors Climbed.
- Title Tesim:
- Accuracy of the Charge HR Fitbit : Step Count, Distance, Heart Rate, and Floors Climbed.
- Abstract Tesim:
- A number of wearable fitness tracking monitors have been marketed in recent years. One device, Fitbit Inc. claims that it offers some of the most advanced technology that allows for accurate measurements of physical activity. However, studies are needed to verify these claims and to demonstrate the actual validity of these devices. Thus, the purpose of this study was to determine the accuracy of the Charge HR Fitbit in terms of step count, distance covered, heart rate, and floors climbed.
- Creator:
- Ritchey, Gabrielle (HC 2017)
- Date:
- 2017
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 17-077
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2017
9. Acting Moliere’s The Misanthrope.
- Title Tesim:
- Acting Moliere’s The Misanthrope.
- Abstract Tesim:
- Before auditioning for the main role of Alceste in Moliere’s The Misanthrope, I was only pre-exposed to Moliere’s position in theatre history and his plays in the classroom and one professional production of The Miser on stage in London’s West End. Hanover College’s courses prepared the important background I needed to understand the influences and styles of writing that make up Moliere’s body of work. Of course, I have sampled at least two or three of his plays on paper; however, seeing one of his farces on stage during my Shakespeare course in London gave me a better understanding of how these three hundred year old farces could still be effectively produced today. I had the chance to be exposed to how directors can take these humorously over the top moments and direct their actors to work these scenes and bring these classical characters to life but still connect with a modern audience. My live example was not The Misanthrope but The Miser, and I only read The Misanthrope one previous time before encountering my role as Alceste on the stage. What I learned in the classroom and experienced in the theater would help guide me, but studying the piece and its characters was a must before I felt confident taking on what would be my biggest role in a Hanover College production.
- Creator:
- Hedges, Michael (HC 2018)
- Date:
- 2018
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS 18-27
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2018
10. The Acute Effect of the Percussive Massage Treatment on Physical Recovery
- Title Tesim:
- The Acute Effect of the Percussive Massage Treatment on Physical Recovery
- Abstract Tesim:
- This study examined the effects of the percussive massage (PM) treatment on physical recovery of pain and delayed onset muscle soreness (DOMS) after a lat pull-down exercise. Ten untrained female Hanover College students, who do not exercise regularly, served as participants. All subjects completed two trials which were randomized and balanced. Subjects were randomly assigned to one of the two different conditions: two minutes of percussive massage treatment applied to the arms or no percussive massage treatment. Subjects completed the remaining trial after a week of rest. It was hypothesized that delayed onset muscle soreness, as determined by range of motion (ROM), will be reduced by the percussive massage treatment versus no percussive massage treatment and visual analogue scale (VAS) will increase with both percussive massage treatment and no treatment, but less with PM treatment. Data collection indicates that the PM treatment was not found (p > 0.05) to be significantly different compared to no recovery intervention after 24 hours and 48 hours as measured by ROM. Muscle soreness ratings with PM intervention were found to be significantly lower (p < 0.05) compared to no recovery intervention after 48 hours. Muscle soreness was lower (20%) after 24 hours post-exercise with the application of the percussive massage gun compared to no recovery intervention. Data concluded (1) there was no significant change in ROM with the use of the PM treatment. (2) Muscle soreness ratings through the VAS were sufficiently lower compared to no PM treatment after 48 hours post-exercise. Although there was not a significant difference in ROM there was still a small decrease of muscle soreness with the use of the PM intervention.
- Creator:
- Panduro Ramirez, Jahaira (HC 2024)
- Rights statement:
- http://rightsstatements.org/vocab/InC/1.0/
- License Tesim:
- https://creativecommons.org/licenses/by-nc-nd/4.0/
- Language:
- English
- Publisher:
- Hanover College
- Identifier:
- IS24_15
- Type:
- Capstone Project
- Keyword:
- Senior Thesis
- Date Created:
- 2024